Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats

Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats

Prolonged neonatal febrile seizures (FSs) often lead to cognitive decline and increased risk of psychopathology in adulthood. However, the neurobiological mechanisms underlying the long-term adverse effects of FSs remain unclear. In this study, we exposed rat pups to hyperthermia and induced FSs las...

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Bibliographic Details
Main Authors: Alexandra V. Griflyuk, Tatyana Y. Postnikova, Aleksey V. Zaitsev
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
febrile seizures
hyperthermia
long-term potentiation
astrocyte
hippocampus
Online Access:https://www.mdpi.com/1422-0067/23/20/12224

Internet

https://www.mdpi.com/1422-0067/23/20/12224

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