Bioengineering of Cytochrome P450 OleT<sub>JE</sub>: How Does Substrate Positioning Affect the Product Distributions?

The cytochromes P450 are versatile enzymes found in all forms of life. Most P450s use dioxygen on a heme center to activate substrates, but one class of P450s utilizes hydrogen peroxide instead. Within the class of P450 peroxygenases, the P450 OleT<sub>JE</sub> isozyme binds fatty acid s...

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Bibliographic Details
Main Authors: Fabián G. Cantú Reinhard, Yen-Ting Lin, Agnieszka Stańczak, Sam P. de Visser
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/11/2675