Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view

Abstract Neurodegenerative diseases, such as Alzheimer’s disease (AD) and various types of amyloidosis, are incurable; therefore, understanding the mechanisms of amyloid decomposition is crucial to develop an effective drug against them for future therapies. It has been reported that one out of thre...

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Bibliographic Details
Main Authors: Adriana Żyła, Anne Martel, Przemysław Jurczak, Augustyn Moliński, Aneta Szymańska, Maciej Kozak
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47514-w