Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release

Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release

Background and Aim: Polyrotaxanes are molecular necklaces composed of polymers, threaded macrocycles, and bulky stopper molecules to inhibit the decomposition of the first two. These supramolecular assemblies are promising active ingredients for treating lysosomal storage disorders. This study aimed...

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Bibliographic Details
Main Authors: Gergely Kali, Alexander H. Mayer, Dennis To, Martyna Truszkowska, Raphael Plangger, Markus Gallei, Andreas Bernkop-Schnürch
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Cyclodextrin
Poly(ethylene glycol)
Polyrotaxane
Cellular uptake
Disulfide stopper molecules
Online Access:http://www.sciencedirect.com/science/article/pii/S266689392400166X

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http://www.sciencedirect.com/science/article/pii/S266689392400166X

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