Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease

Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is associated with the aggregation of the amyloid β protein (Aβ). Aβ oligomers are currently thought to be the major neurotoxic agent responsible for disease development and progression. Thus, their elimination is highly desir...

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Bibliographic Details
Main Authors: Janine Kutzsche, Sarah Schemmert, Markus Tusche, Jörg Neddens, Roland Rabl, Dagmar Jürgens, Oleksandr Brener, Antje Willuweit, Birgit Hutter-Paier, Dieter Willbold
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
Alzheimer’s disease
amyloid β
Aβ oligomers
oral treatment
transgenic mice
">d-enantiomeric peptides
large-scale
cognition
Online Access:https://www.mdpi.com/1420-3049/22/10/1693

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https://www.mdpi.com/1420-3049/22/10/1693

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