MicroRNA-218-5p regulates inflammation response via targeting TLR4 in atherosclerosis

MicroRNA-218-5p regulates inflammation response via targeting TLR4 in atherosclerosis

Abstract Background To investigate the expression of miR-218-5p in atherosclerosis patients and its effect on ox-LDL induced THP-1-derived macrophage inflammatory response. Methods RT-qPCR detected the expression of serum miR-218-5p, and the diagnostic value of miR-218-5p was analyzed by ROC curve....

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Bibliographic Details
Main Authors: Jiajuan Chen, Zusheng Tang, Zhen Chen, Yunjie Wei, Hui Liang, Xiaoqiao Zhang, Zhen Gao, Hezhong Zhu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Atherosclerosis
MiR-218-5p
TLR4
Inflammation response
Online Access:https://doi.org/10.1186/s12872-023-03124-y

Internet

https://doi.org/10.1186/s12872-023-03124-y

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