Improved Safety and Anti-Glioblastoma Efficacy of CAT3-Encapsulated SMEDDS through Metabolism Modification

Improved Safety and Anti-Glioblastoma Efficacy of CAT3-Encapsulated SMEDDS through Metabolism Modification

13<i>a</i>-(<i>S</i>)-3-pivaloyloxyl-6,7-dimethoxyphenanthro(9,10-<i>b</i>)-indolizidine (CAT3) is a novel oral anti-glioma pro-drug with a potent anti-tumor effect against temozolomide-resistant glioma. 13<i>a</i>(<i>S</i>)-3-hydroxyl-6,7-...

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Bibliographic Details
Main Authors: Hongliang Wang, Lin Li, Jun Ye, Wujun Dong, Xing Zhang, You Xu, Jinping Hu, Rubing Wang, Xuejun Xia, Yanfang Yang, Dujia Jin, Renyun Wang, Zhihui Song, Lili Gao, Yuling Liu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
phenanthroindolizidine
self-microemulsifying drug delivery system
metabolism modification
lymphatic transport
Online Access:https://www.mdpi.com/1420-3049/26/2/484

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https://www.mdpi.com/1420-3049/26/2/484

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