Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy

Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy

ABSTRACT Purpose: To investigate the underlying mechanism of hepatic sinusoidal obstruction syndrome (HSOS) induced by Gynura segetum by measuring autophagy in mouse models. Methods: The model group was administered G. segetum (30 g/kg/d) by gavage, while the normal control group was administered...

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Bibliographic Details
Main Authors: Hui Zhang, Shu Jia, Lianyu Jin, Jianzuo Yao MB, Zhihong Shen, Jingyi Wu, Xiaokun Yao, Danwei Chen, Congcong Zhang, Shufang Yu, Ningwei Zhu, Lexiao Jin, Xiaomin Yao
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022-02-01
Series:Acta Cirúrgica Brasileira
Subjects:
Hepatic Veno-Occlusive Disease
Pyrrolizidine Alkaloids
Liver
Autophagy
Mice
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021001100206&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021001100206&tlng=en

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