CiAPEX2 and CiP0, candidates of AP endonucleases in Ciona intestinalis, have 3′-5′ exonuclease activity and contribute to protection against oxidative stress

CiAPEX2 and CiP0, candidates of AP endonucleases in Ciona intestinalis, have 3′-5′ exonuclease activity and contribute to protection against oxidative stress

Abstract Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have been reported, such as AP endonuclease 2 (APEX2) a...

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Bibliographic Details
Main Authors: Masafumi Funakoshi, Daisuke Nambara, Yuichiro Hayashi, Qiu-Mei Zhang-Akiyama
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Genes and Environment
Subjects:
AP endonuclease
Ribosomal protein P0
3′-5′ exonuclease activity
Ciona intestinalis
Online Access:http://link.springer.com/article/10.1186/s41021-017-0087-7

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http://link.springer.com/article/10.1186/s41021-017-0087-7

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