Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of <i>Euphorbia peplus</i> Methanolic Extract in Rats

Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of <i>Euphorbia peplus</i> Methanolic Extract in Rats

This study explored the probable in vivo cardiac and renal toxicities together with in silico approaches for predicting the apoptogenic potential of <i>Euphorbia peplus</i> methanolic extract (EPME) in rats. Cardiac and renal injury biomarkers were estimated with histopathological and im...

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Bibliographic Details
Main Authors: Yasmina M. Abd-Elhakim, Mohamed Abdo Nassan, Gamal A. Salem, Abdelkarim Sasi, Adil Aldhahrani, Khaled Ben Issa, Amany Abdel-Rahman Mohamed
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Toxins
Subjects:
<i>euphorbia peplus</i>
mdm2-p53
apoptosis
anticancer
di-(2-ethylhexyl) phthalate
Online Access:https://www.mdpi.com/2072-6651/11/11/642

Internet

https://www.mdpi.com/2072-6651/11/11/642

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