Modeling and Optimization of the Culture Medium for Efficient 4′-N-Demethyl-Vicenistatin Production by <i>Streptomyces parvus</i> Using Response Surface Methodology and Artificial-Neural-Network-Genetic-Algorithm
4′-N-demethyl-vicenistatin is a vicenistatin analogue that has better antitumor activity with promising applications in the pharmaceuticals industry. The harnessing of the complete potential of this compound necessitates a systematic optimization of the culture medium to enable the cost-effective pr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-03-01
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| Series: | Fermentation |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2311-5637/10/3/154 |