Increasing CB2 Receptor Activity after Early Life Stress Prevents Depressive Behavior in Female Rats
Early adversity, the loss of the inhibitory GABAergic interneuron parvalbumin, and elevated neuroinflammation are associated with depression. Individuals with a maltreatment history initiate medicinal cannabis use earlier in life than non-maltreated individuals, suggesting self-medication. Female ra...
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Format: | Article |
Language: | English |
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MDPI AG
2024-04-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/14/4/464 |