Increasing CB2 Receptor Activity after Early Life Stress Prevents Depressive Behavior in Female Rats

Early adversity, the loss of the inhibitory GABAergic interneuron parvalbumin, and elevated neuroinflammation are associated with depression. Individuals with a maltreatment history initiate medicinal cannabis use earlier in life than non-maltreated individuals, suggesting self-medication. Female ra...

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Bibliographic Details
Main Author: Susan L. Andersen
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/4/464