Spontaneous improvement in randomised clinical trials: meta-analysis of three-armed trials comparing no treatment, placebo and active intervention

<p>Abstract</p> <p>Background</p> <p>It can be challenging for patients and clinicians to properly interpret a change in the clinical condition after a treatment has been given. It is not known to which extent spontaneous improvement, effect of placebo and effect of act...

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Bibliographic Details
Main Authors: Gøtzsche Peter C, Hróbjartsson Asbjørn, Krogsbøll Lasse
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/9/1