Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation

Recognition memory comprises recollection judgment and familiarity, two different processes that engage the hippocampus and the perirhinal cortex, respectively. Previous studies have shown that aged rodents display defective recognition memory and alterations in hippocampal synaptic plasticity. We r...

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Bibliographic Details
Main Authors: Cecilia Hidalgo, Alejandra Arias-Cavieres, Tatiana Adasme, Gina Sánchez, Pablo Muñoz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00111/full