Multi-Oxidant Environment as a Suicidal Inhibitor of Myeloperoxidase

Multi-Oxidant Environment as a Suicidal Inhibitor of Myeloperoxidase

Tissue inflammation drives the infiltration of innate immune cells that generate reactive species to kill bacteria and recruit adaptive immune cells. Neutrophil activation fosters the release of myeloperoxidase (MPO) enzyme, a heme-containing protein generating hypochlorous acid (HOCl) from hydrogen...

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Bibliographic Details
Main Authors: Ramona Clemen, Lara Minkus, Debora Singer, Paul Schulan, Thomas von Woedtke, Kristian Wende, Sander Bekeschus
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Antioxidants
Subjects:
cold physical plasma
enzymatic activity
hydroxyl radical
kINPen
mass spectrometry
MPO
Online Access:https://www.mdpi.com/2076-3921/12/11/1936

Internet

https://www.mdpi.com/2076-3921/12/11/1936

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