Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies

Abstract Multiple genomic and proteomic studies have suggested that peripheral blood mononuclear cells (PBMCs) respond to tumor secretomes and thus could provide possible avenues for tumor prognosis and treatment evaluation. We hypothesized that the chromatin organization of PBMCs obtained from liqu...

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Bibliographic Details
Main Authors: Kiran Challa, Daniel Paysan, Dominic Leiser, Nadia Sauder, Damien C. Weber, G. V. Shivashankar
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00484-8