A newly designed curcumin analog Y20 mitigates cardiac injury via anti-inflammatory and anti-oxidant actions in obese rats.

Obesity is strongly associated with the cause of structural and functional changes of the heart in both human and animal models. Oxidative stress and inflammation play a critical role in the development of obesity-induced cardiac disorders. Curcumin is a natural product from Curcuma Longa with multi...

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Bibliographic Details
Main Authors: Yuanyuan Qian, Peng Zhong, Dandan Liang, Zheng Xu, Melissa Skibba, Chunlai Zeng, Xiaokun Li, Tiemin Wei, Lianpin Wu, Guang Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364772?pdf=render