LC/MS/MS and GC/MS/MS metabolic profiling of Leontodon hispidulus, in vitro and in silico anticancer activity evaluation targeting hexokinase 2 enzyme

LC/MS/MS and GC/MS/MS metabolic profiling of Leontodon hispidulus, in vitro and in silico anticancer activity evaluation targeting hexokinase 2 enzyme

Abstract Leontodon hispidulus Boiss is a wild annual plant growing in Egypt. The present study aims for the first time, to evaluate the phytochemical profile of the main secondary metabolites of the optimized ethanolic extract of the plant using Quadrupole Time-of-Flight Liquid chromatography-mass s...

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Bibliographic Details
Main Authors: Noha Mokhtar Abd-El-Aziz, Mohamed Saeed Hifnawy, Rehab Ahmed Lotfy, Inas Youssef Younis
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Leontodon hispidulus Boiss.
Prostate carcinoma
LC-qToF-MS
GC–MS/MS
Hexokinase-2 enzyme
Online Access:https://doi.org/10.1038/s41598-024-57288-4

Internet

https://doi.org/10.1038/s41598-024-57288-4

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