Lead compound discovery using pharmacophore-based models of small-molecule metabolites from human blood as inhibitor cellular entry of SARS-CoV-2

Context: The development of emerging viral diseases like SARS-CoV-2 has underlined the critical need for new antiviral medicines. Many of the discovered inhibitors have off-target effects or toxicity issues, but no single lead chemical has been found as a powerful SARS-CoV-2 inhibitor. Small-molecul...

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Bibliographic Details
Main Authors: Ellin Febrina, Aiyi Asnawi
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2023-09-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
Online Access:https://jppres.com/jppres/pdf/vol11/jppres23.1688_11.5.810.pdf