Polymeric Amorphous Solid Dispersions of Dasatinib: Formulation and Ecotoxicological Assessment

Polymeric Amorphous Solid Dispersions of Dasatinib: Formulation and Ecotoxicological Assessment

Dasatinib (DAS), a potent anticancer drug, has been subjected to formulation enhancements due to challenges such as significant first-pass metabolism, poor absorption, and limited oral bioavailability. To improve its release profile, DAS was embedded in a matrix of the hydrophilic polymer polyvinylp...

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Bibliográfalaš dieđut
Váldodahkkit: Katarina Sokač, Martina Miloloža, Dajana Kučić Grgić, Krunoslav Žižek
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2024-04-01
Ráidu:Pharmaceutics
Fáttát:
dasatinib
mechanochemical activation
amorphous solid dispersion
drug release
ecotoxicological evaluation
Liŋkkat:https://www.mdpi.com/1999-4923/16/4/551

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https://www.mdpi.com/1999-4923/16/4/551

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