Effects of tranexamic acid on the activity of glutamate transporter EAAT3

Background Tranexamic acid (TXA) is the most widely used hemostatic agent in surgical patients. However, when used in a high dose, it could cause a seizure in the postoperative period. The exact effector mechanism behind the seizure triggering remains unknown. Therefore, the authors investigated the...

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Bibliographic Details
Main Authors: Hyun-Jung Shin, Soo-Young Lee, Hyo-Seok Na, Bon-Wook Koo, Jung-Hee Ryu, Sang-Hwan Do
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2020-07-01
Series:Anesthesia and Pain Medicine
Subjects:
Online Access:http://www.anesth-pain-med.org/upload/pdf/apm-20004.pdf