Rosmarinic Acid Prevents Cisplatin-Induced Liver and Kidney Injury by Inhibiting Inflammatory Responses and Enhancing Total Antioxidant Capacity, Thereby Activating the Nrf2 Signaling Pathway

Rosmarinic Acid Prevents Cisplatin-Induced Liver and Kidney Injury by Inhibiting Inflammatory Responses and Enhancing Total Antioxidant Capacity, Thereby Activating the Nrf2 Signaling Pathway

Drug-induced liver and kidney damage is an emergent clinical issue that should be addressed. Rosmarinic acid (RA) has obvious anti-inflammatory and antioxidant effects, so we evaluated the anti-inflammatory and antioxidant effects of RA pretreatment on serum and liver and kidney tissues of cisplatin...

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Bibliographic Details
Main Authors: Yifei Xiang, Min Ji, Liqin Wu, Li Lv, Qiuling Liang, Ruihan Deng, Zhaoyou Deng, Xia Liu, Lingyi Ren, Xin Feng, Jiakang He
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
acute liver and kidney injury
rosmarinic acid
cisplatin
inflammation
oxidative stress
Nrf2
Online Access:https://www.mdpi.com/1420-3049/27/22/7815

Internet

https://www.mdpi.com/1420-3049/27/22/7815

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