A functional role of Ephrin type-B receptor 6 (EPHB6) in T-cell acute lymphoblastic leukemia

A functional role of Ephrin type-B receptor 6 (EPHB6) in T-cell acute lymphoblastic leukemia

Abstract T-cell lymphoblastic acute leukemia (T-ALL) is an aggressive blood cancer, characterized by restricted cellular subsets with enriched leukemia initiating cells (LICs). Recently, Ephrin receptors (Eph) were described to be highly expressed in cancer stem cells. Here, using public RNA-Seq dat...

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Bibliographic Details
Main Authors: Mattia Colucci, Nadia Trivieri, Gandino Mencarelli, Elisabetta De Santis, Francesca Sansico, Francesco Tamiro, Alberto Visioli, Chiara Barile, Riccardo Pracella, Giovanni Rossi, Elena Binda, Vincenzo Giambra
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Biomarker Research
Subjects:
T-ALL
EphB6
Single-cell RNA-Sequencing
Leukemia-initiating cells (LICs)
Biomarkers
Online Access:https://doi.org/10.1186/s40364-023-00531-3

Internet

https://doi.org/10.1186/s40364-023-00531-3

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