Current In Vitro and In Vivo Models to Study MCPyV-Associated MCC

Merkel cell polyomavirus (MCPyV) is the only human polyomavirus currently known to cause human cancer. MCPyV is believed to be an etiological factor in at least 80% of cases of the rare but aggressive skin malignancy Merkel cell carcinoma (MCC). In these MCPyV+ MCC tumors, clonal integration of the...

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Bibliographic Details
Main Authors: Amanda S. W. Loke, Paul F. Lambert, Megan E. Spurgeon
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/10/2204