BCM3D 2.0: accurate segmentation of single bacterial cells in dense biofilms using computationally generated intermediate image representations

Abstract Accurate detection and segmentation of single cells in three-dimensional (3D) fluorescence time-lapse images is essential for observing individual cell behaviors in large bacterial communities called biofilms. Recent progress in machine-learning-based image analysis is providing this capabi...

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Bibliographic Details
Main Authors: Ji Zhang, Yibo Wang, Eric D. Donarski, Tanjin T. Toma, Madeline T. Miles, Scott T. Acton, Andreas Gahlmann
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-022-00362-4