Synthesis, biological evaluation, molecular docking and in silico ADME studies of phenacyl esters of N-Phthaloyl amino acids as pancreatic lipase inhibitors
In continuation of our previous study, a series of phenacyl esters of N-phthaloyl amino acids were synthesized and screened for their in vitro pancreatic lipase inhibitory activity. N-phthloylation of amino acids and subsequent esterification with different phenacyl bromides in presence of N,N-Dimet...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2018-12-01
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| Series: | Future Journal of Pharmaceutical Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2314724518301043 |