Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-01939-z |