Analysis of ERBB4 Variants in Amyotrophic Lateral Sclerosis Within a Chinese Cohort

Analysis of ERBB4 Variants in Amyotrophic Lateral Sclerosis Within a Chinese Cohort

ERBB4 is related to amyotrophic lateral sclerosis (ALS) in patients with a family history and is thought to cause ALS-19. We screened 448 ALS patients, including 364 sporadic ALS (sALS) and 84 familial ALS (fALS) patients with ERBB4 variants, in a Chinese cohort. In total, 12 missense variants were...

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Bibliographic Details
Main Authors: Fan Wang, Xiangyi Liu, Ji He, Nan Zhang, Lu Chen, Lu Tang, Dongsheng Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neurology
Subjects:
China
amyotrophic lateral sclerosis
ERBB4
variant
clinical features
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.865264/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.865264/full

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