Links between the genetic determinants of morning plasma cortisol and body shape: a two-sample Mendelian randomisation study

Abstract High cortisol production in Cushing’s syndrome leads to fat centralisation. The influence of modest cortisol variations on body shape, however, is less clear. We examined potentially causal associations between morning plasma cortisol and body shape and obesity with inverse-variance weighte...

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Bibliographic Details
Main Authors: Sofia Christakoudi, Alexandros-Georgios Asimakopoulos, Elio Riboli, Konstantinos K. Tsilidis
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-53727-4