Plasma and cerebrospinal fluid cholesterol esterification is hampered in Alzheimer’s disease

Plasma and cerebrospinal fluid cholesterol esterification is hampered in Alzheimer’s disease

Abstract Objective The purpose of this study was to evaluate cholesterol esterification and HDL subclasses in plasma and cerebrospinal fluid (CSF) of Alzheimer’s disease (AD) patients. Methods The study enrolled 70 AD patients and 74 cognitively normal controls comparable for age and sex. Lipoprotei...

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Bibliographic Details
Main Authors: Marta Turri, Elisa Conti, Chiara Pavanello, Francesco Gastoldi, Marcella Palumbo, Franco Bernini, Vittoria Aprea, Francesca Re, Alberto Barbiroli, Davide Emide, Daniela Galimberti, Lucio Tremolizzo, Francesca Zimetti, Laura Calabresi, AGAINST-AD Group
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
High-density lipoproteins
Lecithin:cholesterol acyltransferase
Cholesterol efflux
Apolipoprotein E
Online Access:https://doi.org/10.1186/s13195-023-01241-6

Internet

https://doi.org/10.1186/s13195-023-01241-6

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