Japanese Encephalitis Virus Infected Human Monocyte-Derived Dendritic Cells Activate a Transcriptional Network Leading to an Antiviral Inflammatory Response

Japanese Encephalitis Virus Infected Human Monocyte-Derived Dendritic Cells Activate a Transcriptional Network Leading to an Antiviral Inflammatory Response

A comprehensive understanding of the human immune response to virus infection is imperative for developing effective therapies, antivirals, and vaccines. Dendritic cells (DCs) are among the first cells to encounter the virus and are also key antigen-presenting cells that link the innate and adaptive...

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Bibliographic Details
Main Authors: Shailendra Chauhan, Deepak Kumar Rathore, Shilpa Sachan, Sebastien Lacroix-Desmazes, Nimesh Gupta, Amit Awasthi, Sudhanshu Vrati, Manjula Kalia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Japanese encephalitis virus
flavivirus
monocyte-derived dendritic cell
innate immune response
NF-κB
Tregs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.638694/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.638694/full

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