Lineage Tracking the Generation of T Regulatory Cells From Microbial Activated T Effector Cells in Naïve Mice

Lineage Tracking the Generation of T Regulatory Cells From Microbial Activated T Effector Cells in Naïve Mice

Regulatory T cells (Tregs) are essential for the maintenance of gut homeostasis by suppressing conventional CD4+ helper T cells (Tconvs) that are activated by microbial antigens. Although thymus is the major source of the peripheral Tregs, peripheral conversion from Tconvs to Tregs have also been sh...

Full description

Bibliographic Details
Main Authors: Kun Zhu, Chenfeng He, Si-Qi Liu, Mingjuan Qu, Tao Xie, Xiaofeng Yang, Lei Lei, Xiaobo Zhou, Lin Shi, Dan Zhang, Yanbin Cheng, Yae Sun, Huiqiang Zheng, Xiaonan Shen, Qijing Li, Ning Jiang, Baojun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
tolerance
inducible Tregs
microbiota
gut
TCR repertoire
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03109/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03109/full

Similar Items