ThrRS-Mediated Translation Regulation of the RNA Polymerase III Subunit RPC10 Occurs through an Element with Similarity to Cognate tRNA ASL and Affects tRNA Levels

Aminoacyl tRNA synthetases (aaRSs) are a well-studied family of enzymes with a canonical role in charging tRNAs with a specific amino acid. These proteins appear to also have non-canonical roles, including post-transcriptional regulation of mRNA expression. Many aaRSs were found to bind mRNAs and re...

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Bibliographic Details
Main Authors: Ofri Levi, Monalisha Mallik, Yoav S. Arava
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/2/462