NNAN: Nearest Neighbor Attention Network to Predict Drug–Microbe Associations

NNAN: Nearest Neighbor Attention Network to Predict Drug–Microbe Associations

Many drugs can be metabolized by human microbes; the drug metabolites would significantly alter pharmacological effects and result in low therapeutic efficacy for patients. Hence, it is crucial to identify potential drug–microbe associations (DMAs) before the drug administrations. Nevertheless, trad...

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Bibliographic Details
Main Authors: Bei Zhu, Yi Xu, Pengcheng Zhao, Siu-Ming Yiu, Hui Yu, Jian-Yu Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
deep learning
bipartite graph network
link prediction
drug–microbe association
attention matrix
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.846915/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.846915/full

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