Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein

Abstract Dimethyl sulfoxide (DMSO) is a highly utilized small molecule that serves many purposes in scientific research. DMSO offers unique polar, aprotic and amphiphilic features, which makes it an ideal solvent for a wide variety of both polar and nonpolar molecules. Furthermore, DMSO is often use...

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Bibliographic Details
Main Authors: Lasse Reimer, Caroline Haikal, Hjalte Gram, Vasileios Theologidis, Gergo Kovacs, Harm Ruesink, Andreas Baun, Janni Nielsen, Daniel Erik Otzen, Jia-Yi Li, Poul Henning Jensen
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07706-2