Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients

Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients

Citrullinated neoepitopes have emerged as key triggers of autoantibodies anti-citrullinated protein antibodies (ACPA) synthesis in rheumatoid arthritis (RA) patients. Apart from their critical role in homeostasis and thrombosis, platelets have a significant contribution to inflammation as well. Alth...

Full description

Bibliographic Details
Main Authors: Minjie Xu, Rong Du, Wenping Xing, Xueting Chen, Jian Wan, Shengqing Wang, Li Xiong, Kutty Selva Nandakumar, Rikard Holmdahl, Hui Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
citrullination
platelets
anti-citrullinated protein antibodies (ACPA)
platelet derived microparticles (PDP)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1084283/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1084283/full

Similar Items