Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer

Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer

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Germ cell tumors present contrasting biological and molecular features compared to many solid tumors, which may partially explain their unusual sensitivity to chemotherapy. Reduced DNA repair capacity and enhanced induction of apoptosis appear to be key factors in the sensitivity of germ cell tumors...

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Bibliographic Details
Main Authors: F. Selle, J. Gligorov, S. Richard, A. Khalil, I. Alexandre, D. Avenin, S. Provent, D.G. Soares, J.P. Lotz
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
High-dose chemotherapy
Germ cell tumors
Stem cell transplantation
Solid tumors
Breast cancer
Ovarian cancer
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000100013&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000100013&lng=en&tlng=en

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