High-throughput screening for optimizing adoptive T cell therapies

Abstract Adoptive T cell therapy is a pivotal strategy in cancer immunotherapy, demonstrating potent clinical efficacy. However, its limited durability often results in primary resistance. High-throughput screening technologies, which include both genetic and non-genetic approaches, facilitate the o...

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Bibliographic Details
Main Authors: Yuchen Zhang, Qinglong Xu, Zhifei Gao, Honghao Zhang, Xiaoling Xie, Meifang Li
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-024-00580-w