Intact provirus and integration sites analysis in acute HIV-1 infection and changes after one year of early antiviral therapy

Intact provirus and integration sites analysis in acute HIV-1 infection and changes after one year of early antiviral therapy

Background and objectives: HIV-1 provirus integration in host genomes provides a lifelong reservoir of virally infected cells. Although not able to generate viral progeny, the expression of defective proviruses has been associated with activation. Provirus integration may influence host gene transcr...

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Bibliographic Details
Main Authors: Gabriella Rozera, Giuseppe Sberna, Giulia Berno, Cesare Ernesto Maria Gruber, Emanuela Giombini, Pietro Giorgio Spezia, Nicoletta Orchi, Vincenzo Puro, Annalisa Mondi, Enrico Girardi, Francesco Vaia, Andrea Antinori, Fabrizio Maggi, Isabella Abbate
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Virus Eradication
Subjects:
HIV
Acute infection
Provirus
Integration site
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664022002448

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http://www.sciencedirect.com/science/article/pii/S2055664022002448

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