Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

Abstract Background A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain more effectively than HA alone in pa...

Full description

Bibliographic Details
Main Authors: Cesare Stagni, Martina Rocchi, Alessandro Mazzotta, Nicolandrea Del Piccolo, Nicola Rani, Marco Govoni, Leonardo Vivarelli, Francesca Veronesi, Milena Fini, Dante Dallari
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Musculoskeletal Disorders
Subjects:
Knee osteoarthritis
Knee function
Hyaluronic acid
KSS
Knee pain
PN-HPT™
Online Access:https://doi.org/10.1186/s12891-021-04648-0

Internet

https://doi.org/10.1186/s12891-021-04648-0

Similar Items