The Origin Recognition Complex: From Origin Selection to Replication Licensing in Yeast and Humans

Understanding human DNA replication through the study of yeast has been an extremely fruitful journey. The minichromosome maintenance (MCM) 2–7 genes that encode the catalytic core of the eukaryotic replisome were initially identified through forward yeast genetics. The origin recognition complexes...

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Bibliographic Details
Main Authors: Bik-Kwoon Tye, Yuanliang Zhai
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/1/13