Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cell...

Full description

Bibliographic Details
Main Authors: Maria Bogdanova, Arsenii Zabirnyk, Anna Malashicheva, Daria Semenova, John-Peder Escobar Kvitting, Mari-Liis Kaljusto, Maria del Mar Perez, Anna Kostareva, Kåre-Olav Stensløkken, Gareth J Sullivan, Arkady Rutkovskiy, Jarle Vaage
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
aortic valve
interstitial cells
endothelial cells
calcification
animal models
calcified aortic valve disease
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.835825/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.835825/full

Similar Items