Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cell...

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Bibliographic Details
Main Authors:	Maria Bogdanova, Arsenii Zabirnyk, Anna Malashicheva, Daria Semenova, John-Peder Escobar Kvitting, Mari-Liis Kaljusto, Maria del Mar Perez, Anna Kostareva, Kåre-Olav Stensløkken, Gareth J Sullivan, Arkady Rutkovskiy, Jarle Vaage
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Pharmacology
Subjects:	aortic valve interstitial cells endothelial cells calcification animal models calcified aortic valve disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.835825/full

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