Homoharringtonine Inhibits Allergic Inflammations by Regulating NF-κB-miR-183-5p-BTG1 Axis

Homoharringtonine Inhibits Allergic Inflammations by Regulating NF-κB-miR-183-5p-BTG1 Axis

Homoharringtonine (HHT) is a drug for treatment of chronic myeloid leukemia. However, the role of HHT in allergic inflammations remains unknown. Mouse model of atopic dermatitis (AD) induced by 2, 4,-dinitroflurobenzene (DNFB) and anaphylaxis employing 2,4-dinitropheny-human serum albumin (DNP-HSA)...

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Bibliographic Details
Main Authors: Misun Kim, Hyein Jo, Yoojung Kwon, Youngmi Kim, Hyun Suk Jung, Dooil Jeoung
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
anaphylaxis
atopic dermatitis
BTG1
homoharringtonine
miR-183-5p
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01032/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01032/full

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