Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Elise Ishida et al. generate human monoclonal antibodies that can selectively recognize specific oligosaccharide epitopes of the polysaccharides arabinomannan and lipoarabinomannan, which are critical for M. tuberculosis pathogenesis. The authors demonstrate the utility of these antibodies in both d...

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Bibliographic Details
Main Authors: Elise Ishida, Devin T. Corrigan, Ryan J. Malonis, Daniel Hofmann, Tingting Chen, Anita G. Amin, Delphi Chatterjee, Maju Joe, Todd L. Lowary, Jonathan R. Lai, Jacqueline M. Achkar
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02714-w

Internet

https://doi.org/10.1038/s42003-021-02714-w

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