Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Mutation and natural selection shape the genetic variation in natural populations. Here, we directly estimated the spontaneous mutation rate by sequencing new Drosophila mutation accumulation lines maintained with minimal natural selection. We inferred strong stabilizing natural selection on quantit...

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Bibliographic Details
Main Authors: Wen Huang, Richard F Lyman, Rachel A Lyman, Mary Anna Carbone, Susan T Harbison, Michael M Magwire, Trudy FC Mackay
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
mutation accumulation
genome sequencing
gene expression
stabilizing selection
Online Access:https://elifesciences.org/articles/14625

Internet

https://elifesciences.org/articles/14625

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