An Evolutionarily Conserved SoxB-Hdac2 Crosstalk Regulates Neurogenesis in a Cnidarian

An Evolutionarily Conserved SoxB-Hdac2 Crosstalk Regulates Neurogenesis in a Cnidarian

SoxB transcription factors and histone deacetylases (HDACs) are each major players in the regulation of neurogenesis, but a functional link between them has not been previously demonstrated. Here, we show that SoxB2 and Hdac2 act together to regulate neurogenesis in the cnidarian Hydractinia echinat...

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Bibliographic Details
Main Authors: Hakima Flici, Christine E. Schnitzler, R. Cathriona Millane, Graham Govinden, Amy Houlihan, Stephanie D. Boomkamp, Sanbing Shen, Andreas D. Baxevanis, Uri Frank
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
nervous system
regeneration
transcription factor
SoxB
histone deacetylase
Hdac2
Hydractinia
evolution
cnidaria
neurogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300554

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http://www.sciencedirect.com/science/article/pii/S2211124717300554

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