Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity

Dengue virus replicates its single-stranded RNA genome in membrane-bound complexes formed on the endoplasmic reticulum, where viral non-structural proteins (NS) and RNA co-localize. The NS proteins interact with one another and with the host proteins. The interaction of the viral helicase and protea...

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Bibliographic Details
Main Authors: Satyamurthy Kundharapu, Tirumala Kumar Chowdary
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/8/1712