Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer

Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer

Different pathological conditions, including viral infections and cancer, can have a massive impact on the endoplasmic reticulum (ER), causing severe damage to the cell and exacerbating the disease. In particular, coronavirus infections, including SARS coronavirus-2 (SARS-CoV-2), responsible for COV...

Full description

Bibliographic Details
Main Authors: Anna Tesei, Michela Cortesi, Martina Bedeschi, Noemi Marino, Giacomo Rossino, Roberta Listro, Daniela Rossi, Pasquale Linciano, Simona Collina
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
sigma 1 receptor (S1R)
endoplasmic reticulum (ER)
ER stress
terminal UPR
P2Y<sub>12</sub> inhibitors
ticlopidine
Online Access:https://www.mdpi.com/1420-3049/27/14/4327

Internet

https://www.mdpi.com/1420-3049/27/14/4327

Similar Items