Synthesis, Molecular Docking Studies and ADME Prediction of Some New Albendazole Derivatives as α-Glucosidase Inhibitors

Synthesis, Molecular Docking Studies and ADME Prediction of Some New Albendazole Derivatives as α-Glucosidase Inhibitors

A series of novel 2-(substituted arylidene)-N-(5-(propylthio)-2,3-dihydro-1H-benzo[d]imidazol-2-yl)hydrazine-1-carboxamide derivatives 3a–i were synthesized via condensation of N-(5-(propylthio)-1H-benzo[d]imidazol-2-yl) hydrazinecarboxamide (2), with the corresponding ketone or aldehydes. The chemi...

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Bibliographic Details
Main Authors: Sevil Senkardes, Necla Kulabas, Sukriye Guniz Kucukguzel
Format: Article
Language:English
Published: Slovenian Chemical Society 2022-09-01
Series:Acta Chimica Slovenica
Subjects:
benzimidazoles
albendazole
semicarbazones
antidiabetics
α-glucosidase
docking studies.
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/7387

Internet

https://journals.matheo.si/index.php/ACSi/article/view/7387

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